Benadryl is pictured at a home in North Vancouver, B.C., Monday, November, 11, 2019. THE CANADIAN PRESS/Jonathan Hayward

Benadryl is pictured at a home in North Vancouver, B.C., Monday, November, 11, 2019. THE CANADIAN PRESS/Jonathan Hayward

Moving Benadryl behind the counter doesn’t resolve safety concerns: pharmacists

More doctors are warning against older antihistamines, such as the active ingredient in Benadryl

Sally McQuinn once kept her medicine cabinet stocked with Benadryl, the go-to medication to treat her daughter’s multiple allergies: the Ottawa mother of three assumed that because it was sold on pharmacy shelves and didn’t require a prescription, it was safe.

But she was surprised by recent headlines highlighting that a growing number of doctors are warning against the use of older antihistamines, such as diphenhydramine, the active ingredient in Benadryl, because of safety and efficacy concerns.

McQuinn says she will no longer buy Benadryl and instead choose from the number of existing alternatives.

“Nobody wants to choose the one that’s going to have more negative consequences,” she explains.

The Canadian Society of Allergy and Clinical Immunology released a statement in October recommending curbing the use of older first-generation antihistamines in both adults and children. They said newer antihistamines, including Reactine, Aerius, and Claritin, are safer.

Long-known side effects from standard doses of Benadryl include sedation, cognitive impairment, and possible heart rhythm abnormalities.

Children are particularly at risk of severe consequences, such as seizures and coma, from too high a dose, and research suggests teens using Benadryl for allergies have lower scores on exams than their peers.

The CSACI statement called on regulators to consider moving Benadryl and other first-generation antihistamines from pharmacy shelves to behind the counter in order to force an interaction with pharmacists who can explain the issues and suggest alternatives.

Pharmacists, however, say the solution isn’t so simple: putting Benadryl behind the counter, they say, is not practical and won’t resolve the safety concerns. And they have the same concerns about many other over-the-counter drugs.

READ MORE: Canadian allergists’ group wants Benadryl behind the counter due to side effects

Consumers would have to speak to a pharmacist, who could decline to provide the medication. But since the drug is approved by Health Canada and is well known, many consumers, will continue to push for it, says pharmacist Barry Power, a spokesman for the Canadian Pharmacists Association.

That can create conflict at the drugstore, he adds.

“For many people, the side effect profile isn’t a big concern. But if Benadryl were to come on the market today, it might require a prescription, because of the safety profile,” he says.

Benadryl’s maker, Johnson & Johnson says the products are approved by Health Canada and “when used as directed, are safe and effective.”

In a statement, Health Canada said products containing diphenhydramine meet the requirements and regulations of the Food and Drugs Act. It says it is assessing the allergists’ recent statement “to determine if further risk mitigation measures for diphenhydramine-containing products are required.”

The agency says that it continues to monitor scientific and medical information as it evolves and would take action if this information required a change to “the regulatory status of products containing diphenhydramine.”

Currently, Benadryl is approved for sale without a prescription in locations where a pharmacist is present. This means that it can be sold in pharmacies and certain grocery stores, but not in convenience stores or gas stations.

Nardine Nakhla, a pharmacist who teaches at the University of Waterloo in Ontario, says moving all the diphenhydramine-containing drugs behind the counter is “unrealistic … due to the sheer number of products that contain these problematic ingredients.”

Nakhla says there are also many other drugs, besides diphenhydramine, that have similar risk profiles and are available on pharmacy shelves.

Power agrees that the issue of which drugs belong behind the counter “becomes a bigger question as you start looking (at it).”

– Dr. Michelle Ward is a pediatrician at the Children’s Hospital of Eastern Ontario and associate professor at the University of Ottawa

The Canadian Press

Like us on Facebook and follow us on Twitter

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

Crews had a lot to clean up and they are still working (file photo)
Power restored for the Valley after winter storm

All Bella Coola customers are now out of the dark

Highway 20 is now open but conditions are still challenging (Dawson Road Maintenance photo)
Some customers still without power as additional crews brought in to help

Trees continued to fall onto lines even after the actual storm had passed

The exposure occurred on 24th, 25th, & 26th November 2020, and affects Grade 7, 8, 9, 10 (file photo)
COVID-19 case confirmed at Acwsalcta School

The exposure occurred on 24th, 25th, & 26th November 2020, and affects Grade 7, 8, 9, 10.

A convoy of vehicles passes through Heckman Pass on Highway 20 as cleanup operations continued Saturday. Dawson Road Maintenance is asking motorists to watch for crews and equipment working throughout the area. (Dawson Road Maintenance photo/Facebook)
Highway 20 reopens between Anahim Lake and Bella Coola after winter storm Friday

“We appreciate your patience as we continue to clear wood debris and widen sections of the road.”

(Needpix.com)
Pandemic has ‘exacerbated’ concerns for B.C. children and youth with special needs: report

Pandemic worsened an already patchwork system, representative says

Cannabis bought in British Columbia (Ashley Wadhwani/Black Press Media)
Is it time to start thinking about greener ways to package cannabis?

Packaging suppliers are still figuring eco-friendly and affordable packaging options that fit the mandates of Cannabis Regulations

Janet Austin, the lieutenant-governor of British Columbia, not seen, swears in Premier John Horgan during a virtual swearing in ceremony in Victoria, Thursday, Nov. 26, 2020. Horgan says he will look to fill gaps in the federal government’s sick-pay benefits program aimed at preventing the spread of COVID-19. THE CANADIAN PRESS/Jonathan Hayward
B.C. premier says province prepared to patch holes in new federal sick-pay benefits

Horgan said workers should not be denied pay when they are preventing COVID-19’s spread

Provincial health officer Dr. Bonnie Henry updates B.C.’s coronavirus situation at the legislature, Nov. 30, 2020. (B.C. government)
Hockey team brought COVID-19 back from Alberta, B.C. doctor says

Dr. Bonnie Henry pleads for out-of-province travel to stop

B.C. Premier John Horgan on a conference call with religious leaders from his B.C. legislature office, Nov. 18, 2020, informing them in-person church services are off until further notice. (B.C. government)
B.C. tourism relief coming soon, Premier John Horgan says

Industry leaders to report on their urgent needs next week

Most Read