Genomics allows individualize treatments for cancer patients, explains Dr. Howard Lim, medical oncologist, BC Cancer.

Breaking down cancer with genomics

Donor funding has played a pivotal role in advancing genomics research

“It was like a miracle.”

Trish Keating was diagnosed with colon cancer in 2010 and after surgery, chemotherapy and radiation treatment, she was told in 2013 when her cancer returned that it was terminal.

After enrolling in the Personalized Onco-Genomics (POG) Program at BC Cancer, the team of experts discovered Trish’s cancer was driven by a specific protein. They then identified and administered an existing blood pressure medication that is known to block pathways to that protein.

The results were rapid and dramatic: eight weeks after starting her new treatment, Trish was tumour-free.

“It’s still so hard to believe,” says Trish. “I was months away from death.”

Trish’s experience is just one example of how genomics – where experts deploy whole genome analysis to inform individual treatment planning for patients – is transforming cancer care for people across B.C.

“The use of genomics is trying to understand the blueprint – what we call the genome – to a cancer, and by understanding that blueprint we can then start to individualize treatments for patients,” says Dr. Howard Lim, medical oncologist, BC Cancer. “Genomics will change not only how we treat cancer, but also how we detect and prevent cancer.”

Cancer genomes are as unique as a fingerprint, and no two genomes are identical. Therefore, says Dr. Lim, cancer treatment can no longer be one-size-fits-all.

“We’re beginning to understand that not all cancers are the same and certain ones respond differently to different treatments, or don’t respond at all to particular treatments,” he says. “With this knowledge we can begin to tailor the type of chemotherapy or targeted agents that we can use for treating specific cancers.”

Dr. Lim says donor funding has played a pivotal role in advancing genomics research, which is also the fundraising focus of BC Cancer Foundation’s Inspiration Gala on Nov. 2.

“The basic science we do to help further all of this research is thanks to donor support – it makes a huge impact to all of us in the clinic,” says Dr. Lim. “In fact, a lot of the research and treatments we’ve moved forward with is because of BC Cancer Foundation donors.”

You can help transform the standard of cancer care with genomically informed treatments for British Columbians facing cancer. Learn more at www.bccancerfoundation.com.

Just Posted

BC SPCA team helps discover new feline virus after outbreak at Quesnel shelter

Fechavirus is a kind of parvovirus, which makes cats and kittens very sick

COVID-19 highlights lack of connectivity in First Nations communities

Many don’t have access required to utilize online platforms, says First Nations Technology Council

Commercial salmon fisheries delayed for Bella Coola area

DFO notice says Area C gill net fisheries in Area 8 have been delayed until June 15

Pacific Coastal won’t open until community is ready

The company has suspended operations until further notice

11 new COVID-19 cases in B.C. as top doc urges caution amid ‘encouraging’ low rates

Dr. Bonnie Henry also announced that two care home outbreaks would be declared over

Surrey mayor’s party under fire for ‘sickening’ tweet accusing northern B.C. RCMP of murder

Mayor Doug McCallum says tweet, Facebook post ‘sent out by unauthorized person’

Father’s Day Walk Run for prostate cancer will be virtual event this year throughout B.C.

The annual fundraiser for Prostate Cancer Foundation BC has brought in $2.5 million since 1999

Dr. Bonnie Henry announces official ban on overnight kids’ camps this summer

New ban comes after talking with other provincial health officials across the country, Henry says

Senior man in hospital after unprovoked wolf attack near Prince Rupert

Conservation officers are on site looking for the wolf

VIDEO: NASA astronauts blast off into space on SpaceX rocket

Marks NASA’s first human spaceflight launched from U.S. soil in nearly a decade

‘I knew what he wanted’: Kootenay man spends hours in tree as black bear patrols below

Francis Levasseur is no stranger to the outdoors, but a recent run-in with a bear caused quite a scare

PHOTOS: U.S. cities brace for increasing unrest over police killing of George Floyd

Minnesota Gov. Tim Walz has fully mobilized the state’s National Guard

$200,000 Maybach impounded after ‘L’ driver caught excessively speeding in Vancouver

Meanwhile, the supervisor sat in the passenger seat, police said

Most Read